Author
Utrecht UniversityORCID 0000-0002-8084-8444Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Indu Khatri, Saskia D. van Asten, Leandro F. Moreno…·Iris C. R. M. Kolder
VIBE is an R package that enables pathway-guided RNA-seq analysis for disease stratification and therapeutic targeting in various disorders.
Ewart Kuijk, Francis Blokzijl, Myrthe Jager…·Edwin P. J. G. Cuppen
The paper quantifies somatic mutation accumulation in fetal liver and intestinal stem cells, finding higher mutation rates and distinct mutation spectra in fetal liver compared to fetal intestine and adult tissues.
Myrthe Jager, Francis Blokzijl, Ewart Kuijk…·Edwin P. J. G. Cuppen
The paper shows that NER deficiency increases Signature 8 mutations in specific tissues and suggests this could be a biomarker for NER-deficiency in cancer.
Francis Blokzijl, Roel Janssen, Ruben van Boxtel, Edwin P. J. G. Cuppen
MutationalPatterns analyzes mutational processes genome-wide to quantify mutational signatures and their relation to genomic features.