Brandon W. Higgs

The paper analyzes spatial molecular patterns in liver disease and transplant outcomes using single-cell RNA sequencing data from multiple conditions and post-transplant biopsies.

This study identifies four immune subtype clusters in HNSCC using multi-omics data and shows their association with treatment response and survival.

This study evaluates pathology foundation models for detecting tertiary lymphoid structures in cancer tissues, finding strong performance in PDAC but challenges in HNSCC due to tumor heterogeneity.

This paper introduces an LLM-based framework that predicts synergistic cancer drug combinations using drug data and a knowledge graph, achieving an F1 score of 0.80.

The paper identifies molecular and spatial features of early liver transplant rejection, including primed T-cells, immune synapse activation, and novel drug targets like proteasomal and HSP90 inhibitors.

VIBE is an R package that enables pathway-guided RNA-seq analysis for disease stratification and therapeutic targeting in various disorders.

The paper identifies mediators of improved glycemia after gastric bypass surgery using a high-throughput mediation analysis method applied to plasma proteome and metabolome data.