Author

Wim Verhaegh

Philips (Netherlands)ORCID 0000-0002-8088-9924Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Anja van de StolpeiD· 2 shared Laurent HoltzeriD· 2 shared Henk van Ooijen· 1 shared Jules P.P. Meijerink· 1 shared Kirsten Cante-Barrett· 1 shared Rico Hagelaar· 1 shared Valentina Cordo· 1 shared Yvonne J.W. Wesseling-RozendaaliD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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2 shared papersDevelopmental Biology

Anja van de StolpeORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintApr 14, 2021

Measurement of activity of developmental signal transduction pathways to quantify stem cell pluripotency and phenotypically characterize differentiated cells

Yvonne J.W. Wesseling-Rozendaal, Laurent Holtzer, Wim Verhaegh, Anja van de Stolpe

The paper quantifies stem cell pluripotency and differentiation states by measuring activity of developmental signaling pathways across different cell types and culture conditions.

3 citations

humanbulk RNA-seq

Cancer BiologyCancersPeer-reviewedOct 27, 2020

Development of a Notch pathway assay and quantification of functional Notch pathway activity in T-cell acute lymphoblastic leukemia

Kirsten Cante-Barrett, Laurent Holtzer, Henk van Ooijen…·Jules P.P. Meijerink

The paper develops a Notch pathway activity assay using mRNA levels of direct NOTCH target genes and shows that high activity correlates with better event-free survival in T-cell acute lymphoblastic leukemia patients.

DOI 10.3390/cancers12113142

humanbulk RNA-seq