Anja van de Stolpe

Probing the transcriptome response to shivering in skeletal muscle using a multilayered bioinformatics approach

The paper analyzes the transcriptomic response of human skeletal muscle to repeated shivering using bioinformatics approaches, identifying a sex-specific transcriptional signature that diminishes with cold adaptation.

Measurement of activity of developmental signal transduction pathways to quantify stem cell pluripotency and phenotypically characterize differentiated cells

The paper quantifies stem cell pluripotency and differentiation states by measuring activity of developmental signaling pathways across different cell types and culture conditions.

Development of a Notch pathway assay and quantification of functional Notch pathway activity in T-cell acute lymphoblastic leukemia

The paper develops a Notch pathway activity assay using mRNA levels of direct NOTCH target genes and shows that high activity correlates with better event-free survival in T-cell acute lymphoblastic leukemia patients.