Loss of factor VIII in zebrafish rebalances antithrombin deficiency but has a limited bleeding diathesis
Catherine E. Richter, Azhwar Raghunath, Megan S Griffin, Murat Yaman, Valder R. Arruda, Benjamin J. Samelson‐Jones, Jordan A. Shavit
The paper shows that loss of FVIII in zebrafish reduces antithrombin deficiency but does not significantly cause bleeding, suggesting a unique hemostatic balance.
bioRxiv · Feb 28, 2024 · PreprintGenetics