Murat Yaman

This paper uses a zebrafish model to identify genetic modifiers of thrombosis, finding a novel mutation in prothrombin and additional modifiers like factor X and plasminogen.

This study identifies novel small molecules that prevent LPS-induced endotoxemia in zebrafish, showing that dabigatran protects through a thrombin-independent mechanism.

This study uses zebrafish to screen FDA-approved drugs for antithrombotic effects, identifying thyroid hormone and others as potential treatments for VTE subtypes.

The paper shows that loss of FVIII in zebrafish reduces antithrombin deficiency but does not significantly cause bleeding, suggesting a unique hemostatic balance.