Author

Conor James McClune

Howard Hughes Medical InstituteORCID 0000-0002-8119-4278Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:matrix factorization· 1 Assay:metabolomics· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Chloe WickiD· 2 shared Chun‐Ting LiuiD· 2 shared Elizabeth S. SattelyiD· 2 shared Polly Morrell FordyceiD· 2 shared Anish SomaniiD· 1 shared Bernd Markus LangeiD· 1 shared Ricardo De La PeñaiD· 1 shared Shou‐Ling XuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Chloe WickORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMar 24, 2026

FoTO1 orchestrates Taxol biosynthesis through catalytic and non-catalytic mechanisms

Chloe Wick, Anish Somani, Chun‐Ting Liu…·Elizabeth S. Sattely

This paper identifies FoTO1 as a dual-function enzyme that enhances Taxol biosynthesis through catalytic conversion and non-catalytic organization of P450s in plants.

2 citations

plant (other)experimental assay

𝕏 PostBluesky

BiochemistryNaturePeer-reviewedJun 11, 2025

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Multiplexed perturbation of yew reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors

Conor James McClune, Chun‐Ting Liu, Chloe Wick…·Elizabeth S. Sattely

A multiplexed perturbation and single-nucleus RNA-seq screen of Taxus needles found eight new Taxol pathway genes, including FoTO1, enabling baccatin III and a late Taxol precursor in N. benthamiana.

105 citationstop 1%

plant (other)snRNA-seq

𝕏 PostBluesky