Benchmarking atlas-level data integration in single-cell genomics
Malte D. Luecken, Maren Büttner, Kridsadakorn Chaichoompu…·Fabian Joachim Theis
BBKNN, Scanorama, and scVI lead complex scRNA-seq integration in a 38-setup, nine-task, 14-metric benchmark; highly variable gene selection helps, whereas scaling favors batch removal over bio-conservation.