Anavaj Sakuntabhai

This study compares genomic signatures of natural selection across Senegalese, Thai, and Peruvian populations to identify immune-related adaptive variants with implications for region-specific vaccine development.

The paper identifies and functionally characterizes regulatory variants in DPP9 associated with severe COVID-19 by analyzing genetic risk factors and their impact on gene expression and immune cell function.

The paper compares the modular organization of SKAP1 and SKAP2 to understand how they interact with SRC kinases and the evolutionary implications of these interactions.

This study identifies factors influencing DNA methylation variation in human blood, showing that cytomegalovirus infection and aging drive methylation changes, with cellular composition and DNA sequence as key predictors.

The paper identifies novel genetic and non-genetic factors associated with plasma protein levels in healthy donors, highlighting their impact on immune response variability.

This study shows that genetic diversity in Collaborative Cross mice affects ZIKV infection outcomes, including viral replication and disease severity, independent of Oas1b.

IPCAPS is an R package that uses iterative pruning PCA to resolve fine-scale population structure from SNP data, improving subpopulation detection and reducing misclassification.

The paper introduces IPCAPS, an unsupervised clustering method using iterative pruning to detect fine-scale population structure from SNP data, showing improved accuracy over existing tools in simulations.