ImmunologyThe Journal of ImmunologyPeer-reviewed
Antigen presentation requirements for effective cDC1-based cancer immunotherapy
Josue Estiven Pineda, Tomoyuki Minowa, Li Shen…·Matthew M. Gubin
This study shows that in vitro-derived cDC1s resemble tumor-infiltrating DCs and that MHC-I and MHC-II antigen presentation by these cells is essential for effective cancer immunotherapy.