Cancer BiologyPLoS ONEPeer-reviewed
Computationally accelerated identification of P-glycoprotein inhibitors
Lauren A McCormick, James W. McCormick, Chanyang Park…·Pia D. Vogel
This study identifies nine novel P-gp inhibitors using a computationally accelerated drug discovery pipeline, showing they reverse multidrug resistance in cancer cells with minimal toxicity to non-cancerous cells.