Author

Lauren A McCormick

Southern Methodist UniversityORCID 0000-0001-9164-0932Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

April L. RisingeriD· 1 shared Chanyang ParkiD· 1 shared Courtney A. Follit· 1 shared Ezekiel C. ThomasiD· 1 shared James W. McCormickiD· 1 shared John G. WiseiD· 1 shared Kristen J. VerheyiD· 1 shared Lynne Blasius· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

April L. RisingerORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 2, 2026

Taccalonolide AJ uncouples tubulin GTP hydrolysis from microtubule depolymerization

Ezekiel C. Thomas, Nicholas E. Vangos, Lauren A McCormick…·Michael A. Cianfrocco

This study shows that taccalonolide AJ stabilizes microtubules through a mechanism distinct from paclitaxel, promoting a compacted, post-GTP hydrolysis state that resists depolymerization.

DOI 10.64898/2026.09.30.755716

experimental assay

𝕏 PostBluesky

Cancer BiologyPLoS ONEPeer-reviewedAug 13, 2025

Computationally accelerated identification of P-glycoprotein inhibitors

Lauren A McCormick, James W. McCormick, Chanyang Park…·Pia D. Vogel

This study identifies nine novel P-gp inhibitors using a computationally accelerated drug discovery pipeline, showing they reverse multidrug resistance in cancer cells with minimal toxicity to non-cancerous cells.

8 citations

humanCITE-seq

𝕏 PostBluesky