Author

Valerio Castoldi

ORCID 0000-0002-8136-3422Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Angelo IannielliiD· 1 shared Dario Di SilvestreiD· 1 shared Edoardo Niccolò BelliniiD· 1 shared Gabriele OrdazzoiD· 1 shared Greta Rossi· 1 shared Letizia BernardoiD· 1 shared Letizia LeocaniiD· 1 shared Mirko LuoniiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Angelo IannielliORCID

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1 paper

Recent·Most cited

MCT1-dependent energetic failure and neuroinflammation underlie optic nerve degeneration in Wolfram syndrome mice

Greta Rossi, Gabriele Ordazzo, Niccolò N Vanni, Valerio Castoldi, Angelo Iannielli, Dario Di Silvestre, Edoardo Niccolò Bellini, Letizia Bernardo, Serena Gea Giannelli, Mirko Luoni, Sharon Muggeo, Letizia Leocani, Pierluigi Mauri, Vania Broccoli

This study identifies MCT1-dependent metabolic failure and neuroinflammation as key factors in optic nerve degeneration in Wolfram syndrome mice, suggesting therapeutic targets for early intervention.

eLife · Jan 16, 2023Peer-reviewedNeuroscience