Author

Greta Rossi

Vita-Salute San Raffaele University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Vania BroccoliiD· 2 shared Angelo IannielliiD· 1 shared Dario Di SilvestreiD· 1 shared Edoardo Niccolò BelliniiD· 1 shared Fabio ManentiiD· 1 shared Federica CuozzoiD· 1 shared Gabriel SiracusanoiD· 1 shared Gabriele OrdazzoiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Vania BroccoliORCID

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2 papers

Recent·Most cited

A WFS1 variant disrupting acceptor splice site uncovers the impact of alternative splicing on β cell apoptosis in a patient with Wolfram syndrome.

Raniero Chimienti, Silvia Torchio, Gabriel Siracusano, Valentina Zamarian, Laura Monaco, Marta Tiffany Lombardo, Silvia Pellegrini, Fabio Manenti, Federica Cuozzo, Greta Rossi, Paola Carrera, Valeria Sordi, Vania Broccoli, Riccardo Bonfanti, Giorgio Casari, , Lorenzo Piemonti

This study investigates how a WFS1 splice site mutation affects β cell apoptosis in Wolfram syndrome by analyzing alternative splicing and functional consequences in patient-derived iPSCs.

bioRxiv · Dec 29, 2023 · PreprintGenetics

MCT1-dependent energetic failure and neuroinflammation underlie optic nerve degeneration in Wolfram syndrome mice

Greta Rossi, Gabriele Ordazzo, Niccolò N Vanni, Valerio Castoldi, Angelo Iannielli, Dario Di Silvestre, Edoardo Niccolò Bellini, Letizia Bernardo, Serena Gea Giannelli, Mirko Luoni, Sharon Muggeo, Letizia Leocani, Pierluigi Mauri, Vania Broccoli

This study identifies MCT1-dependent metabolic failure and neuroinflammation as key factors in optic nerve degeneration in Wolfram syndrome mice, suggesting therapeutic targets for early intervention.

eLife · Jan 16, 2023Peer-reviewedNeuroscience