Edoardo Niccolò Bellini

This study introduces TES, an epigenetic silencer targeting YAP/TAZ-TEAD axis in GBM, which suppresses tumor growth and invasiveness while being safe for normal cells.

MargheRita streamlines MS-DIAL output analysis and metabolite identification in R by providing a comprehensive pipeline for LC-MS/MS data, enhancing fragment matching accuracy with a curated spectral library.

This study identifies MCT1-dependent metabolic failure and neuroinflammation as key factors in optic nerve degeneration in Wolfram syndrome mice, suggesting therapeutic targets for early intervention.

The paper shows that SET levels influence enhancer usage during cell fate acquisition, leading to altered gene regulation and contributing to disease.