Long-Term Functional 3D Human Skeletal Muscle Constructs from Human Induced Pluripotent Stem Cells Enable Electrically Controlled Remodelling Studies
Cintia Rivares, Niek Klein Hofmeijer, Emanuele Feola, Jeroen Rouwkema, Massimo Sartori
This study develops 3D human skeletal muscle constructs from hiPSCs that can undergo electrically controlled remodelling, showing distinct morphological and force-generating responses to different mechanical boundary conditions.
bioRxiv · Aug 28, 2025 · PreprintBioengineering