Author

Roberta Azzarelli

Wellcome/MRC Cambridge Stem Cell InstituteORCID 0000-0002-8160-7538Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna PhilpottiD· 1 shared Jethro Lundie-BrowniD· 1 shared John-Poul Ng-BlichfeldtiD· 1 shared Rosalind DrummondiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperDevelopmental Biology

Anna PhilpottORCID

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1 paper

Recent·Most cited

Developmental BiologybioRxivPreprintApr 24, 2026

Chromatin priming and co-factor availability shape lineage response to the neuronal pioneer factor ASCL1 in pluripotency

Jethro Lundie-Brown, Rosalind Drummond, John-Poul Ng-Blichfeldt…·Anna Philpott

The paper shows that ASCL1's ability to induce a neuronal program in pluripotent cells depends on chromatin priming and co-factor availability, with PHOX2B enhancing neuronal differentiation.

DOI 10.64898/2026.03.19.712999

mouseChIP-seq

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