Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
Maik Müller, Fabienne Gräbnitz, Niculò Barandun, Yang Shen, Fabian Wendt, Sebastian N. Steiner, Yannik Severin, Stefan U. Vetterli, Milon Mondal, James R. Prudent, Raphael Hofmann, Marc van Oostrum, Roman C. Sarott, Alexey I. Nesvizhskii, Erick M. Carreira, , Bernd Wollscheid
This paper introduces LUX-MS, a light-triggered optoproteomic technology to map surfaceome receptor interactions and nanoscale organization, revealing insights into intercellular signaling and drug action.
Nature Communications · Dec 2, 2021Peer-reviewedSystems Biology