Erick M. Carreira

The paper demonstrates the use of a photoswitchable cannabinoid, azo-THC-3, to suppress seizures in a mouse model by local photoactivation in the hippocampus, avoiding systemic side effects.

This paper develops a TR-FRET-based assay to measure ligand binding kinetics for CB1R and CB2R, finding that D77 enables accurate determination of on- and off-rates for various agonists and antagonists.

This paper introduces a novel GR degrader, KH-103, which selectively degrades glucocorticoid receptors and shows improved efficacy over existing inhibitors.

This paper introduces LUX-MS, a light-triggered optoproteomic technology to map surfaceome receptor interactions and nanoscale organization, revealing insights into intercellular signaling and drug action.