Gualtiero Alvisi

This study identifies a mutation-tolerant bipartite NLS in ΔNp63α that ensures nuclear import and transcriptional activity despite mutations.

This study uses CRISPR/Cas9 to disrupt mutant TP63 alleles in patient-derived cells, improving corneal epithelial proliferation in EEC syndrome.

The paper identifies a classical NLS in Black Sea Bass Polyomavirus LTA that mediates nuclear import via Importin α/β1, distinct from mammalian PyVs.

The paper identifies two nuclear localization signals in the Anelloviridae capsid protein ORF1, showing their distinct roles in subcellular localization and evolutionary adaptation.