BiochemistrybioRxivPreprint
Molecular dynamics simulations reveal the impact of Ser295 phosphorylation on the structure of pyrin domain-containing NOD-like receptor 3
Christina F. Sandall, Justin A. MacDonald
The paper uses molecular dynamics simulations to show that Ser295 phosphorylation in NLRP3 alters its structure, affecting ATPase activity and inflammasome assembly.
DOI 10.1101/2025.05.28.656610