Author

Alexander Ewe

Leipzig UniversityORCID 0000-0002-8252-1605Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Achim Aigner· 1 shared Andrej BenjakiD· 1 shared Anke AugspachiD· 1 shared Antonio Rodríguez-CaleroiD· 1 shared Charlotte Komarek· 1 shared Claire Kennedy DietrichiD· 1 shared Cristina ZivkoiD· 1 shared Dilara AkhoundovaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Achim Aigner

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 13, 2025

Blocking Minor Intron Splicing Disrupts DNA Repair and Overcomes Therapy Resistance in Prostate and Breast Cancer

Anke Augspach, Paola Francica, Kaitlin N. Girardini…·Mark A. Rubin

This study shows that targeting the minor spliceosome, specifically U6atac snRNA, disrupts DNA repair and overcomes therapy resistance in prostate and breast cancers.

DOI 10.64898/2025.12.10.693392

humanDNA methylation

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