David B. Shackelford

This study identifies PPARG as a key regulator of adipogenic differentiation in liposarcoma, showing its loss contributes to the aggressive phenotype of dedifferentiated liposarcoma.

Genetic deletion or pharmacological inhibition of ferroptosis suppressor protein 1 (FSP1) induces lipid peroxidation and restricts lung adenocarcinoma growth in vivo, establishing FSP1 as a therapeutic vulnerability.

This study identifies OGDHL as a regulator of tumor growth, neuroendocrine marker expression, and nucleotide abundance in prostate cancer, with implications for treatment resistance.

This study uses multiple particle tracking to analyze brain ECM structure changes and predicts neurodevelopmental age using machine learning.