The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2
Adam D Longhurst, Kyle E. Wang, Harsha Garadi Suresh, Mythili Ketavarapu, Henry N. Ward, Ian Richard Jones, Vivek Narayan, Frances V Hundley, Arshia Zernab Hassan, Charles M. Boone, Chad L. Myers, Yin Shen, Vijay Ramani, Brenda Andrews, David Paul Toczyski
The paper identifies PRC2.1's role in opposing G1 progression by regulating CCND1 and CCND2, showing its importance in cell proliferation across multiple cancer types.
bioRxiv · Mar 18, 2024Molecular Biology