Peter Meerlo

This paper shows that vardenafil, a PDE5 inhibitor, can reverse sleep deprivation-induced amnesia in mice when combined with optogenetic engram stimulation, enhancing memory reactivation in the dentate gyrus.

This study shows that sleep deprivation does not cause memory loss but suboptimal storage, which can be retrieved using optogenetics or roflumilast.

This study shows that sleep deprivation reduces specific spine types on certain dendritic branches in CA1 neurons, but not others, suggesting branch-specific effects on structural plasticity.