Author

Massimo Domenico Sammito

AstraZeneca (United Kingdom)ORCID 0000-0002-8346-9247Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Adam J. SimpkiniD· 1 shared Airlie J. McCoyiD· 1 shared Andrei N. LupasiD· 1 shared Claudia MillániD· 1 shared Daniel John RigdeniD· 1 shared Darren J. SchofieldiD· 1 shared Davide AngelettiiD· 1 shared Joana PereiraiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Adam J. SimpkinORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Integrated single-cell analyses of affinity-tested B-cells enable the identification of a gene signature to predict antibody affinity.

Michele Chirichella, Matthew Ratcliff, Shuang Gu, Ricardo J. Miragaia, Massimo Domenico Sammito, Valentina Cutano, Suzanne E. Cohen, Davide Angeletti, Xavier Romero Ros, Darren J. Schofield

The paper identifies a transcriptomic signature, 'High Signature', that predicts high-affinity antibodies from B-cells without sequence analysis.

Cell Systems · Feb 1, 2026Peer-reviewedImmunology

Assessing the utility of CASP14 models for molecular replacement

Claudia Millán, Ronan M. Keegan, Joana Pereira, Massimo Domenico Sammito, Adam J. Simpkin, Airlie J. McCoy, Andrei N. Lupas, Marcus D. Hartmann, Daniel John Rigden, Randy J. Read

This paper evaluates CASP14 models for molecular replacement using a new metric, reLLG, which is independent of diffraction data and shows AlphaFold2 models outperform others.

Proteins Structure Function and Bioinformatics · Aug 12, 2021Peer-reviewedBioinformatics