Author

Darren J. Schofield

AstraZeneca (United Kingdom)ORCID 0000-0001-6367-2347Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Davide AngelettiiD· 1 shared Massimo Domenico SammitoiD· 1 shared Matthew RatcliffiD· 1 shared Michele ChirichellaiD· 1 shared Ricardo J. MiragaiaiD· 1 shared Shuang Gu· 1 shared Suzanne E. Cohen· 1 shared Valentina CutanoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Davide AngelettiORCID

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1 paper

Recent·Most cited

ImmunologyCell SystemsPeer-reviewedFeb 1, 2026

Integrated single-cell analyses of affinity-tested B-cells enable the identification of a gene signature to predict antibody affinity.

Michele Chirichella, Matthew Ratcliff, Shuang Gu…·Darren J. Schofield

The paper identifies a transcriptomic signature, 'High Signature', that predicts high-affinity antibodies from B-cells without sequence analysis.

2 citationstop 4%

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