Liang Yu

Cafe provides an integrated platform for cell fate analysis, unifying data storage, methods, benchmarking, and visualization to improve trajectory inference and interpretation.

SCROAM accurately estimates cell type abundance in bulk tissues using single-cell references and domain adaptation, outperforming existing methods in multiple datasets.

This study identifies linifanib as a potential anti-necroptosis agent for sepsis through bioinformatics and experimental validation.

The paper introduces a topology-based method to connect fragmented disease modules and demonstrates its application on curated diseases and multi-omics data.

ORF Capture-Seq enables targeted full-length isoform sequencing by using cloned ORFs as probes, significantly increasing isoform detection compared to unenriched samples.

This paper introduces STAM, a method using multi-layer networks to identify drug treatment patterns by analyzing tissue-specific PPI networks and drug-target modules.