BiophysicsPLoS ONEPeer-reviewed
Cnot4 heterozygosity attenuates high fat diet-induced obesity in mice and impairs PPARγ-mediated adipocyte differentiation.
Tomokazu Yamaguchi, Midori Hoshizaki, Yumiko Imai…·Keiji Kuba
This study shows that Cnot4 heterozygosity reduces obesity in mice on a high-fat diet by impairing PPARγ-mediated adipocyte differentiation without affecting metabolic gene expression or serum levels.
5 citations