Yumiko Imai

The paper develops a semi-automated Ribo-Seq and Disome-Seq platform to analyze translation status across many samples, identifying factors regulating translation and revealing links between stop codon readthrough and mitochondrial translation deficiency in COVID-19.

This study shows that Cnot4 heterozygosity reduces obesity in mice on a high-fat diet by impairing PPARγ-mediated adipocyte differentiation without affecting metabolic gene expression or serum levels.

The paper analyzes single-cell immune data from healthy individuals to reveal cell diversity and daily fluctuations, showing how immune responses vary between individuals and over time.