Zahra Rattray

This study characterizes the developability of IgG3 mAbs using computational and experimental methods, finding poorer stability and higher viscosity compared to IgG1.

This study presents a framework for computationally screening mutations to modify antibody viscosity, showing that hydrophobic and electrostatic patches significantly affect viscosity, with positive charges causing the most increase.

The paper integrates mass-spectrometry-based metabolomics and proteomics to identify molecular sub-phenotypes of senescence induced by different stressors.