Craig Jamieson

Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments

The paper shows that breast cancer micrometastases alter metabolism to change extracellular vesicle production, creating an invasive microenvironment.

A first insight into the developability of an IgG3: A combined computational and experimental approach

This study characterizes the developability of IgG3 mAbs using computational and experimental methods, finding poorer stability and higher viscosity compared to IgG1.

A type IV Autotaxin inhibitor ameliorates acute liver injury and non-alcoholic steatohepatitis in mice

This study evaluates a type IV ATX inhibitor, Cpd17, showing improved efficacy over a type I inhibitor in reducing liver injury in mouse models of acute liver injury and non-alcoholic steatohepatitis.