Author

Matthias Leung

University of MinnesotaORCID 0000-0002-8378-8272Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Glenn Prazere LoboiD· 2 shared Rakesh RadhakrishnaniD· 2 shared Anjelynt LoriD· 1 shared Drew Yochim· 1 shared Heidi RoehrichiD· 1 shared Scott W. McPhersoniD· 1 shared Swati S. MoreiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Glenn Prazere LoboORCID

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2 papers

Recent·Most cited

Cell BiologyFASEB BioAdvancesPeer-reviewedAug 1, 2025

Rescue of the Stargardt Disease phenotype in Abca4 knockout mice through dietary modulation of the vitamin A receptor RBPR2

Rakesh Radhakrishnan, Matthias Leung, Drew Yochim…·Glenn Prazere Lobo

This study shows that dietary beta-carotene reduces lipofuscin accumulation in Stargardt disease mice by modulating the vitamin A receptor RBPR2.

2 citations

mouseexperimental assay

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Cell BiologyThe FASEB JournalPeer-reviewedMar 10, 2025

Loss of the systemic vitamin A transporter RBPR2 affects the quantitative balance between chromophore and opsins in visual pigment synthesis

Rakesh Radhakrishnan, Matthias Leung, Anjelynt Lor…·Glenn Prazere Lobo

This study shows that loss of RBPR2 affects retinoid homeostasis and visual pigment synthesis, leading to visual function defects in mice under vitamin A deficiency.

6 citations

mousebulk RNA-seq

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