Author

Arash Shahsavari

Wellcome/MRC Cambridge Stem Cell InstituteORCID 0000-0002-8396-3958Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2

Frequent Co-Authors

Irina I MohorianuiD· 4 shared Andi MunteanuiD· 2 shared Marion PerriniD· 2 shared Brandon Tyler WesleyiD· 1 shared Carola Maria MorelliD· 1 shared Casey Allison Rimland· 1 shared Cédric GhevaertiD· 1 shared Christopher A. PenfoldiD· 1 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersBioinformatics

Irina I MohorianuORCID

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Author profile →

4 papers

Recent·Most cited

Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

Carola Maria Morell, Samantha Grace Tilson, Rute Alexandra Tomaz, Arash Shahsavari, Andi Munteanu, Giovanni Canu, Brandon Tyler Wesley, Marion Perrin, Imbisaat Geti, Subhankar Mukhopadhyay, Francesca Mazzacuva, Paul Gissen, Jose Garcia-Bernardo, Martin Bachman, Casey Allison Rimland, , Ludovic Vallier

This paper develops a 3D multicellular model of NAFLD using hiPSC-derived liver cells to study disease mechanisms and interactions.

bioRxiv · Feb 7, 2024 · PreprintCell Biology

The sum of two halves may be different from the whole. Effects of splitting sequencing samples across lanes.

Eleanor C Williams, Ruben Chazarra-Gil, Arash Shahsavari, Irina I Mohorianu

This paper investigates how splitting sequencing samples across lanes affects results in bulk and single-cell sequencing, showing reduced detail and potential bias in analyses.

Genes · Dec 1, 2022Peer-reviewedBioinformatics

Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells

Moyra Lawrence, Arash Shahsavari, Susanne Bornelöv, Thomas Moreau, Rebecca McDonald, Thomas M. Vallance, Katarzyna Kania, Maike Paramor, James Baye, Marion Perrin, M. Steindel, Paula Jimenez-Gomez, Christopher A. Penfold, Irina I Mohorianu, Cédric Ghevaert

This study maps in vitro megakaryocyte progenitor states to their in vivo counterparts and identifies surface markers for their purification.

Science Advances · Feb 16, 2022Peer-reviewedDevelopmental Biology

ClustAssess: tools for assessing the robustness of single-cell clustering

Arash Shahsavari, Andi Munteanu, Irina I Mohorianu

ClustAssess evaluates clustering robustness in single-cell data by analyzing algorithmic and technical impacts on cell-type identification.

bioRxiv · Jan 31, 2022 · PreprintBioinformatics