Generation of functional hepatocytes by forward programming with nuclear receptors
Rute A. Tomaz, Ekaterini D. Zacharis, Fabian Bachinger, Annabelle Wurmser, Daniel Yamamoto, Sandra Petrus-Reurer, Carola Maria Morell, Dominika Dziedzicka, Brandon Tyler Wesley, Imbisaat Geti, Charis‐Patricia Segeritz, Miguel Cardoso de Brito, Mariya Chhatriwala, Daniel Ortmann, Kourosh Saeb‐Parsy, Ludovic Vallier
This study generates functional hepatocytes from human pluripotent stem cells using forward programming with nuclear receptors, bypassing the limitations of traditional differentiation methods.
eLife · Jul 26, 2022Peer-reviewedDevelopmental Biology