Winner-Takes-All Resource Competition Redirects Cascading Cell Fate Transitions
Rong Zhang, Hanah Goetz, Juan Ramon Melendez-Alvarez, Jiao Li, Tian Ding, Xiao Wang, Xiao‐Jun Tian
The paper demonstrates a 'winner-takes-all' resource competition in synthetic gene circuits, showing how it redirects cell fate transitions and proposes a division of labor strategy to mitigate its effects.
Nature Communications · Feb 8, 2021Peer-reviewedSynthetic Biology