Zhidong Gao

In situ Discovery of Immune Repertoire Reveals Antitumor Immunity and Therapeutic Antibodies

This paper introduces Archimap, a spatial transcriptomic platform that profiles immune repertoires and microbiota in FFPE tissues, revealing antitumor immunity and therapeutic antibodies.

Multimodal AI for Single cfDNA Profiling and Cancer Screening

The paper develops a Transformer-based model called cfAI to profile and detect cancer-derived cfDNA by integrating methylation, fragmentomics, and histone modifications, achieving high sensitivity and specificity in multi-cancer detection.

Systematic Benchmarking of High-Throughput Subcellular Spatial Transcriptomics Platforms

The paper benchmarks five high-throughput subcellular spatial transcriptomics platforms using multi-omics data from cancer samples, evaluating performance across multiple metrics.