Author

Adeline E. Williams

National Institute of Allergy and Infectious DiseasesORCID 0000-0002-8433-0060Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Irma Sánchez-VargasiD· 2 shared Ken E. OlsoniD· 2 shared Alexander BergmaniD· 1 shared Alexander Crosbie-Villaseca· 1 shared Alexander W. E. FranziD· 1 shared Alongkot PonlawatiD· 1 shared André Luis Costa‐da‐SilvaiD· 1 shared Andrea Gloria‐SoriaiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenomics

Irma Sánchez-VargasORCID

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2 papers

Recent·Most cited

Global genomics of Aedes aegypti unveils widespread and novel persistent infectious viruses capable of triggering a small RNA response

Shruti Gupta, Rohit Sharma, Adeline E. Williams, Irma Sánchez-Vargas, Noah H. Rose, Chao Zhang, Alexander Crosbie-Villaseca, Zheng Zhu, Gargi Dayama, Andrea Gloria‐Soria, Doug E. Brackney, Jessica E. Manning, Sarah S. Wheeler, Angela Caranci, Trinidad Reyes, , Nelson C. Lau

The paper identifies novel persistent viruses in Aedes aegypti mosquitoes using small RNA sequencing and confirms their replication and transmissibility in cell lines.

bioRxiv · Jun 6, 2024 · PreprintGenomics

Assessing single-component gene drive systems in the mosquito Aedes aegypti via single generation crosses and modeling

William R Reid, Adeline E. Williams, Irma Sánchez-Vargas, Jingyi Lin, Rucsanda Juncu, Ken E. Olson, Alexander W. E. Franz

This study evaluates CRISPR/Cas9-based gene drive systems in Aedes aegypti by analyzing indel accrual, maternal effects, and fitness costs to model GD fixation rates.

bioRxiv · Dec 8, 2021 · PreprintSynthetic Biology