Shruti Gupta

MPGEM harmonizes and completes gene-expression profiles from legacy microarray datasets, enabling large-scale transcriptomic analysis.

The paper develops a pan-cancer, pan-treatment model to predict drug responses using patient-derived xenografts, showing it works well across cancer types with limited training data.

The paper quantifies transposable element RNA dynamics in aging human and mouse brains and neurodegenerative diseases, finding age-related changes and disease-specific TE RNA dysregulation.

The paper identifies novel persistent viruses in Aedes aegypti mosquitoes using small RNA sequencing and confirms their replication and transmissibility in cell lines.