Author

Young‐Ho Lee

Chungnam National UniversityORCID 0000-0002-8441-5814Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Masaki OkumuraiD· 2 shared Yunseok HeoiD· 2 shared Yuxi LiniD· 2 shared Airu Takeuchi· 1 shared Eiichiro MoriiD· 1 shared Hiroya AbeiD· 1 shared Hiroyuki KumetaiD· 1 shared Hyeongseop JeongiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Masaki OkumuraORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Ca2+-driven PDIA6 phase separation to ensure proinsulin quality control

Young‐Ho Lee, Tomohide Saio, Mai Watabe, Motonori Matsusaki, Shingo Kanemura, Yuxi Lin, Taro Mannen, Tsubura Kuramochi, Yuka Kamada, Katsuya Iuchi, Michiko Tajiri, Kotono Suzuki, Yan Li, Yunseok Heo, Kotone Ishii, , Masaki Okumura

This study shows Ca2+ induces PDIA6 phase separation, enhancing proinsulin folding and preventing aggregation through recruitment of PDIA3.

Nature Cell Biology · Nov 1, 2025Peer-reviewedBiochemistry

Atomistic structure of the interlocking claw-like amyloid fibril of full-length glucagon

Hyeongseop Jeong, Yuxi Lin, Jin Hae Kim, Wookyung Yu, Yunseok Heo, Hyung‐Sik Won, Masaki Okumura, Young‐Ho Lee

The paper reports the atomic structure of glucagon amyloid fibrils using cryo-EM, revealing a dimeric architecture and distinct from previous models.

bioRxiv · Nov 21, 2022 · PreprintMolecular Biology