Author

Samuel Bernard

Lyon 1 UniversitéORCID 0000-0002-8442-9968Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Fabien Crauste AiD· 2 shared Olivier GandrilloniD· 2 shared Thi Nhu Thao Nguyen· 2 shared Catherine Koering· 1 shared Christophe ArpiniD· 1 shared Deborah C. MashiD· 1 shared Elodie ValliniD· 1 shared Embla Steiner· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

Fabien Crauste AORCID

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Author profile →

3 papers

Recent·Most cited

Multiscale modeling of the spatial structure of stem cells in neuroblastoma patient-derived tumoroids reveals a critical role for a short-range diffusive process

Thi Nhu Thao Nguyen, Catherine Koering, Elodie Vallin, Sandrine Gonin-Giraud, Laura Broutier, Samuel Bernard, Fabien Crauste A, Olivier Gandrillon

This study uses a multiscale agent-based model to show that short-range diffusive signaling among stem cells is critical for reproducing the spatial structure of neuroblastoma tumoroids.

PLoS Computational Biology · Mar 31, 2026Peer-reviewedCancer Biology

Effect of Alcohol and Cocaine Abuse on Neuronal and Non-Neuronal Cell Turnover in the Adult Human Hippocampus

Kanar Alkass, Embla Steiner, Samuel Bernard, Tara Wardi Le Maître, Gopalakrishnan Dhanabalan, Mikael Landén, Kirsty L. Spalding, Jonas Frisén, Deborah C. Mash, Henrik Druid

The paper assesses neuronal and non-neuronal cell turnover in the hippocampus of individuals with alcohol or cocaine abuse compared to healthy controls, finding no significant difference in turnover rates between groups.

bioRxiv · Sep 10, 2024 · PreprintNeuroscience

In silico modelling of CD8 T cell immune response links genetic regulation to population dynamics

Thi Nhu Thao Nguyen, Madge Martin, Christophe Arpin, Samuel Bernard, Olivier Gandrillon, Fabien Crauste A

This study models CD8 T cell immune response using a multiscale agent-based approach to link genetic regulation to population dynamics.

bioRxiv · Mar 1, 2024 · PreprintSystems Biology