Author

Tassnim Abdelwahab

Universitätsklinikum WürzburgORCID 0000-0002-8467-2976Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Antoine‐Emmanuel SalibaiD· 2 shared Janos GrohiD· 2 shared Rudolf MartiniiD· 2 shared David Stadler· 1 shared Fabian ImdahliD· 1 shared Konrad KnöpperiD· 1 shared Martin StangeliD· 1 shared Michael P. ColemaniD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Antoine‐Emmanuel SalibaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genetically perturbed myelin as a risk factor for neuroinflammation-driven axon degeneration

Janos Groh, Tassnim Abdelwahab, Yogita Mallu Kattimani, Michaela Hörner, Silke Loserth, Viktoria Gudi, Róbert Adalbert, Fabian Imdahl, Antoine‐Emmanuel Saliba, Michael P. Coleman, Martin Stangel, Mikael Simons, Rudolf Martini

The paper shows that genetically perturbed myelin increases neuroinflammation-driven axon degeneration through immune-glial interactions in mice.

Nature Communications · Oct 30, 2023Peer-reviewedNeuroscience

Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed myelinating oligodendrocytes in PLP1 mutant mice

Tassnim Abdelwahab, David Stadler, Konrad Knöpper, Panagiota Arampatzi, Antoine‐Emmanuel Saliba, Wolfgang Kastenmüller, Rudolf Martini, Janos Groh

The paper identifies cytotoxic CNS-associated T cells as drivers of axon degeneration in PLP1 mutant mice through single-cell transcriptomics and functional experiments.

iScience · Apr 19, 2023Peer-reviewedNeuroscience