Panagiota Arampatzi

This study shows that M-CSF enhances alveolar macrophage function to protect against invasive aspergillosis in immunocompromised mice.

This study models Fabry disease in human sensory neurons and finds axon guidance deficits and reduced neurite length due to Gb3 accumulation, with partial rescue by AGAL enzyme supplementation.

This study shows that IFN-gamma signaling in cardiomyocytes causes metabolic changes in the heart, including increased glucose uptake and reduced oxidative phosphorylation, which resemble changes in aging and heart failure.

The paper examines human dorsal root ganglia (DRG) after plexus injury, finding two types of outcomes: neuronal preservation or loss, with implications for treatment strategies.

The paper identifies cytotoxic CNS-associated T cells as drivers of axon degeneration in PLP1 mutant mice through single-cell transcriptomics and functional experiments.

scSLAM-seq measures transcription dynamics in single cells by distinguishing newly synthesized from pre-existing RNA, revealing stochastic transcription and gene-specific differences.