Cancer BiologybioRxivPreprint
Therapeutic Targeting of the TGFβ Pathway Augments CAR T cell Efficacy in Glioblastoma
Darya Alizadeh, Robyn A. Wong, Madeleine S. Maker…·Christine E. Brown
This study shows that targeting the TGFβ pathway improves CAR T cell efficacy in glioblastoma by enhancing antitumor activity and modulating the tumor microenvironment.