Santiago Ramón‐García

This study evaluates the in vitro pharmacokinetics and pharmacodynamics of TBAJ-587 and its metabolites against M. tuberculosis, showing their efficacy and binding behavior in different media.

The paper introduces OPTIKA, a high-throughput time-kill assay for assessing drug combinations against Mycobacterium tuberculosis, showing it outperforms traditional methods by over 1000-fold.

This study investigates selamectin resistance in Mycobacterium smegmatis and finds that resistance requires specific mutations and intact cell envelope integrity.

This paper identifies sanfetrinem cilexetil as a promising oral beta-lactam antibiotic for tuberculosis treatment through preclinical studies showing its activity against Mtb and potential for repurposing.

This study identifies 4H-pyran-4-ylidenes as antimicrobial compounds from an industrial chemical library active against Gram-positive bacteria, including MRSA, with low cytotoxicity.