Author

Scott L. Carter

Broad InstituteORCID 0000-0002-8480-1475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:variant calling· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Andrew D. CherniackiD· 1 shared Ashton C. BergeriD· 1 shared Barbara Hill Meyers· 1 shared Barbara Tabak· 1 shared Catherine XueiD· 1 shared Coyin OhiD· 1 shared Gad A. GetziD· 1 shared Galen F. GaoiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Andrew D. CherniackORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedJun 11, 2026

Robust discovery of mutational signatures using power posteriors

Catherine Xue, Jeffrey W. Miller, Scott L. Carter, Jonathan H. Huggins

This paper introduces a Bayesian NMF approach with power posteriors and sparsity-inducing priors to improve mutational signature discovery, showing better accuracy than existing methods.

DOI 10.1371/journal.pcbi.1014372

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 5, 2019

The Tangent copy-number inference pipeline for cancer genome analyses

Barbara Tabak, Gordon Saksena, Coyin Oh…·Gad A. Getz

The paper introduces Tangent and Pseudo-Tangent pipelines for copy-number inference from cancer genome data, improving noise reduction and accuracy in SNP array and WES analyses.

5 citations

humanwhole-exome sequencing

𝕏 PostBluesky