Author

Barbara Tabak

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:Hi-C· 1

Frequent Co-Authors

Alexander A. Shishkin· 1 shared Ali PallaiD· 1 shared Amy Y. ChowiD· 1 shared András RabiD· 1 shared Andres D. Chamorro-Parejo· 1 shared Andrew D. CherniackiD· 1 shared Ashton C. BergeriD· 1 shared Barbara Hill Meyers· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenomics

Alexander A. Shishkin

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Author profile →

3 papers

Recent·Most cited

Generation of Region-specific Airway Basal Stem Cells from Human Pluripotent Stem Cells via Regulation of NOGGIN-BMP Axis

Shingo Suzuki, Nicole Sandoval, Shnutez Doddipalli, Dalia M. Hassan, Cristina Barillá, András Rab, Mo-Fan Huang, John M. Avila, Barbara Tabak, Junjie Lu, Peggy P. Hsu, Tristan Frum, Bryan C. Derebery, María José Gacha Garay, Andres D. Chamorro-Parejo, , Sarah X.L. Huang

This study generates region-specific airway basal stem cells from human pluripotent stem cells by modulating the NOGGIN-BMP axis, showing distinct differentiation potentials for proximal and distal airway cell types.

bioRxiv · Oct 1, 2025 · PreprintCell Biology

The Tangent copy-number inference pipeline for cancer genome analyses

Barbara Tabak, Gordon Saksena, Coyin Oh, Galen F. Gao, Barbara Hill Meyers, Michael M. Reich, Steven E. Schumacher, Lindsay C. Westlake, Ashton C. Berger, Scott L. Carter, Andrew D. Cherniack, Matthew M. Meyerson, Rameen Beroukhim, Gad A. Getz

The paper introduces Tangent and Pseudo-Tangent pipelines for copy-number inference from cancer genome data, improving noise reduction and accuracy in SNP array and WES analyses.

bioRxiv · Mar 5, 2019 · PreprintBioinformatics

Higher-order inter-chromosomal hubs shape 3-dimensional genome organization in the nucleus

Sofia A. Quinodoz, Noah Ollikainen, Barbara Tabak, Ali Palla, Jan Marten Schmidt, Elizabeth Detmar, Mason Lai, Alexander A. Shishkin, Prashant Bhat, Yodai Takei, Vickie Trinh, Erik I. Aznauryan, Pamela H. Russell, Christine S. Cheng, Marko Jovanović, , Mitchell Guttman

The paper introduces SPRITE, a method for detecting higher-order DNA interactions, and shows that nuclear bodies act as inter-chromosomal hubs shaping 3D genome organization.

Cell · Jun 7, 2018Peer-reviewedGenomics