Author

Catherine Xue

Broad InstituteORCID 0000-0002-5518-122XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adrianne D. GladdeniD· 1 shared Alon GoreniD· 1 shared Catherine LiiD· 1 shared Chad NusbaumiD· 1 shared Charles B. EpsteiniD· 1 shared Elizabeth GiengeriD· 1 shared Evan M. CornettiD· 1 shared Ido YofeiD· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Adrianne D. GladdenORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedJun 11, 2026

Robust discovery of mutational signatures using power posteriors

Catherine Xue, Jeffrey W. Miller, Scott L. Carter, Jonathan H. Huggins

This paper introduces a Bayesian NMF approach with power posteriors and sparsity-inducing priors to improve mutational signature discovery, showing better accuracy than existing methods.

DOI 10.1371/journal.pcbi.1014372

humanwhole-genome sequencing

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GenomicsEpigenetics & ChromatinPeer-reviewedNov 4, 2016

Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq

Michele Busby, Catherine Xue, Catherine Li…·Alon Goren

This study compares monoclonal and polyclonal antibodies for ChIP-seq of histone modifications, finding monoclonals perform similarly in most cases but show differences for H3K27ac.

38 citations

humanmouse

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