ImmunologybioRxivPreprint
Signaling induced biophysical disruption of repressed chromatin domains drives immune cell fate
Alexia Martínez de Paz, Christopher R. Chin, Mythili Ketavarapu…·Steven Zvi Josefowicz
The paper identifies H3 serine 28 phosphorylation as a mechanism driving chromatin derepression and immune cell fate transitions by disrupting repressive chromatin domains.