Author

Jarne Pauwels

Ghent UniversityORCID 0000-0002-8525-7109Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Kris GevaertiD· 4 shared An StaesiD· 1 shared Andrea ArgentiniiD· 1 shared Ane Olazagoitia‐GarmendiaiD· 1 shared Bruno J. Santacreu· 1 shared Cristina CosentinoiD· 1 shared Cristina Moreno‐CastroiD· 1 shared David CommuniiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersMolecular Biology

Kris GevaertORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 23, 2026

TRMT10A deficiency and tRNA fragmentation disrupt human pancreatic β-cell identity and insulin maturation

Cristina Moreno‐Castro, María Nicol Arroyo, Khadija Benabdallah…·Mariana Igoillo‐Esteve

This study shows TRMT10A deficiency causes β-cell dysfunction by promoting tRNA fragmentation and disrupting PCSK1 expression, leading to impaired insulin maturation and glucose-stimulated insulin secretion.

DOI 10.64898/2026.07.22.739528

humanbulk RNA-seq

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BioinformaticsBioinformaticsPeer-reviewedJun 22, 2026

DiaReport: Reproducible Workflow for Differential Expression Analysis and Interactive Reporting in DIA-based Proteomics

Andrea Argentini, Esperanza Fernández, Jarne Pauwels, Kris Gevaert

DiaReport provides a reproducible workflow for differential expression analysis and interactive reporting in DIA-based proteomics, demonstrating its utility with an extracellular vesicle dataset.

DOI 10.1093/bioinformatics/btag435

proteomicsstatistical model

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Molecular BiologyJournal of Extracellular VesiclesPeer-reviewedJul 1, 2025

A 96well ultrafiltration approach for the high-throughput proteome analysis of extracellular vesicles isolated from conditioned medium

Jarne Pauwels, Tessa Van de Steene, Freya De Muyer…·Kris Gevaert

This paper introduces a 96-well ultrafiltration method for isolating extracellular vesicles from conditioned medium, improving purity and reproducibility for proteomic analysis.

4 citations

proteomicsexperimental assay

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BiochemistryAnalytical ChemistryPeer-reviewedApr 22, 2024

High-throughput nano-flow proteomics using a dual-column electrospray source

An Staes, Katie L. Boucher, Sara Dufour…·Simon Devos

The paper introduces a dual-column electrospray source for nano-flow proteomics to improve throughput while maintaining sensitivity in low-input samples.

6 citations

proteomicsexperimental assay

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